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Before taking tramadol, tell your doctor or pharmacist if you are allergic to it; or to other narcotics (e.g., codeine); or if you have any other allergies.
Tramadol Oral : Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD
If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting tramadol.
Avoid taking MAO inhibitors within 2 weeks before, during, and after treatment with tramadol.
Other medications can affect the removal of tramadol from your body, which may affect how tramadol works or increase the risk of side effects. These drugs include quinidine, azole antifungals (such as ketoconazole), macrolide antibiotics (such as erythromycin), rifamycins (such as rifabutin), drugs used to treat seizures (such as carbamazepine, phenytoin), and St. John's wort. This is not a complete list.